Case Study - Testimony

I was the Research Coordinator for Minicircle’s Phase 1 study. I have advised the company since its formation, and have an advisor stake in it.

As my background is in psychology, I was originally quite skeptical of the results that Minicircle’s founders reported from their initial self-testing of the follistatin vector. I did witness both the CEO and CSO’s body composition shift noticeably after they took their own vector; however, it was unclear if that was fueled by placebo. 

Through my role as Research Coordinator, I have conducted interviews with nearly every human participant in the study, as well as transcribed roughly half of the raw data. Both self reported assessments and the body composition statistical analysis suggest that the treatment has some efficacy, but without a placebo condition, the findings are not conclusive.

After hearing about a reduction of arthritis symptoms in some of the participants, I administered the follistatin vector to my family’s large aged dog, Skye.

Skye had been diagnosed with disc degeneration, and was presumably arthritic. Every other night she would cry out from pain, until some CBD/ibuprofen/etc was given to her. She had been choosing to go on fewer walks, and was getting up to stand less frequently. 

Following administration of the therapy, Skye stopped crying at night and resumed going on walks whenever given the chance. These positive changes have persisted for around a year, but the benefits seem to be declining as of writing.  

I have personally received this treatment as well. I have mild scoliosis. A saw a reduction in the difference between my leg lengths (1cm to .5cm), presumably from the strengthening of spinal muscles. I experienced a mild improvement in energy levels and a reduction in muscle recovery time following strenuous exercise in the ~2 months following the treatment’s administration. 

For all of these reasons, as well as the findings from the in human study, I am optimistic about this treatment being used to treat spinal and joint issues, and potentially increasing healthspan, if not lifespan, in both humans and canines.